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Nanomaterials and continuous wave laser-based efficient desorption for…

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Jae Young Kim, Eun Seok Seoa, Hee Jin Lima, Hyunmin KimORCID logob, Ji-Won Parkc, Hyeon Ho Shind, Dong-Kwon Lim and Dae Won Moon



Micrometer-resolution mass spectrometric imaging of live hippocampal tissue is achieved with a highly efficient desorption of biomolecules using a 532 nm continuous wave laser and gold nanoparticles or graphene oxide as an energy transporter, which enables clear identification of the distributions of monoacylglycerol, adenine, cholesterol, sphingosine and ceramide.





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